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Factors That Increase Chances of Cancer Development in a Person
#1
Among the most dreaded diseases, cancer is one of them and affects different organs or tissues within the body. In the present times, many types of cancers affecting different parts of the body with varied consequences have been unveiled, although the list may not be exhaustive. The different types of cancers affecting different organs or tissues are usually specific to that particular organ or tissue and may not affect any other remote organ or tissue, even though some rare cases may be observed, where a specific type of cancer affects a number of tissues and organs. A number of factors make some people predisposed and susceptible to the development of cancer within their body. Hence, like many other diseases, cancer may be regarded as a multi-factorial disease dependent on a number of factors that are summarized as follows:

a) Age makes some people predisposed to cancer. The advance in age leads to higher probability of development of genetic mistakes, which turns a normal cell into a cancerous one. The continuous exposure to carcinogens or other factors makes a cell prone to genetic changes during cell division that may result in cancerous growths.

b) Genetic makeup of some individuals increases the risk for development of cancer. Cancer results from a number of mutations in the genes of the individuals. These mutations may be inborn or may develop due to environmental factors like long-term exposure to carcinogens, etc. Although, the individuals inborn with genetic mutations may not develop cancer in all the cases, the chances of developing cancer is high among them, the phenomena being known as genetic predisposition. For e.g. the presence of one of the faulty genes BRCA1 and BRCA2 in the some women makes them predisposed to the development of breast cancer. However, the presence of genetic mutations is not always noticed in breast cancer patients that initiates the studies related to the viability of other factors in the cancer development.

c) The immunological system of the individuals has a promising role in the development of different types of cancers. The HIV positive individuals or AIDS patients have higher probability of developing cancer. Some individuals with history of organ transplantation with intake of immune system suppressing drugs for prevention of organ rejection or the individuals with inborn rare medical syndromes affecting immunity are predisposed to cancer development. Cervical cancer, cancers of genital areas, lymphomas, liver cancer, and stomach cancer may develop due to the overlapping of the mentioned conditions. The transplanted cells have the property of continuous cell division that makes them predisposed to develop genetic mistakes resulting in formation of cancerous cells.

d) The exposure to various environmental hazards in the daily life may also lead to cancer development. Different types of pollution, which may be man-made or natural consisting of harmful radiation, tobacco smoke, the ultra-violet rays of the sun, the hazards of work-place, effects of exposure to asbestos, etc are some of the possible reasons related to environment for the development of cancer.

e) Unhealthy lifestyle may also make people predisposed to cancer development. Smoking is one of the main reasons for the development of lung cancer. The intake of red and processed meat with alcohol accompanied with lack of physical activity also lead to predisposition to cancer development. In some cases, unhealthy lifestyle accompanied with eating junk food that may be laden with food additives may also lead to cancer.

f) In the daily life, people are exposed to a number of carcinogens or different cancer causing substances in different forms that may result in the development of cancer in one form or other. However, although everyone is exposed to carcinogens in one form or other, only some people are susceptible to cancer development. It is due to the extent of the influence of other factors.

g) In the development of most of the cancers, virus plays a major role by making genetic changes in the normal cells leading to the formation of cancerous cells e.g. cervical cancer, Lymphomas, T-cell Leukaemia, oro-pharyngeal cancer, etc are some of the cancers that are caused due to different types of viruses.

h) Infection resulting from different types of bacteria may in some cases lead to specific type of cancer for e.g. the stomach cancer results from the inflammation in the mucous lining of the stomach that is caused due to Helicobacter pylori. Different lymphomas of the stomach also result from the bacterial infections of the stomach.

In this way, it is seen that multiple factors play crucial roles in the development of cancer and the presence of some factors are closely linked with high risk making some people predisposed to the disease. Hence, to develop proper therapeutics for the disease, it is essential to consider the influence of all the factors and the possible roles played by them.
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#2
Particular Lifestyle is one of the main causes which may lead to cancer. Such life style includes bad hobbits related to diet, sleep, stress and exercises. Diet is one of the important aspects of healthy life style. Some diets improve health while some affects health. Bad Diet is one of the factors which may trigger a way towards cancer. But the good thing is that lifestyle related factors like diet are preventable. Another important factor of lifestyle is addiction.
Addiction to tobacco, drugs, alcohol etc causes cancers. A person’s lifestyle should be free from any such addiction. It has been estimated that around 50 % of cancers in men are due to consumption of tobacco and other such cancer causing agents. Therefore appropriate changes in lifestyle can reduce the mortality. Diet cause is predominant among cancers of the oesophagus, upper aero digestive tract that is throat and mouth, stomach, large intestine etc.
High fat content food , meat consumption are risk factors while at the same time a diet rich in fruits , green and yellow vegetables protects against many cancers. Food with high anti-oxidants helps in prevention of cancer. High anti-oxidant food includes carrot which contains Beta carotenoid, Dark color fruits and vegetables etc. Consumption of large quantity of red chilies, food at very high temperature and other additions like alcohol consumption together increases the chances of cancer of digestive system like stomach etc.
Apart from this, a lifestyle which is stress free, or has stress depressor helps to increase factors which prevent cancers. Regular exercise of at least 30 minutes a day can significantly reduce risk of cancer as well as other diseases. Thus, Healthy Lifestyle and good dietary habits keeps diseases away !
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