[SunilNagpal]

That sounds interesting! But I doubt if a (DNA) Vaccine can lead to hereditary changes. For that, alterations of germ line cells would be needed, DNA vaccines (yet to be approved for humans) on the other hand target a few cells (soma) of the body.

You may introduce butterfly effect here, with the plot that the altered cells produced the antigen as well as an associate 'unexpected'molecule. The antigen helped in curing the patients/susceptibles, but the 'unexpected molecule' later termed as UMol, could cross the blood brain barrier and had high affinity towards Luteinising hormone. UMol would travel out of brain conjugated to LH and get released in ovaries/testes, where it turned into a DNA repair inhibitor. The progeny of vaccinated persons eventually turned out to be mutants/disabled.......(plot can be extended/manoeuvred...)