Contact: to feature here

by suakka at 05-04-2012, 08:07 AM
enGENEious is a two-day conference on cutting edge research in synthetic biology and biotechnology. This international event has been organised by students and post-docs of the University of Oxford to allow future researchers to meet pioneers who have made outstanding contributions in this field.

Abstract deadline: 30th May 2012; Registration deadline: 30th May 2012

Register for a FLASH TALK to win an iPAD!
by sdurugu at 05-04-2012, 02:03 AM

I am a Masters graduate in Bioengineering with over an year of work experience with a top Biomedical device company in product development. However, I have decided to make a switch to academia to spend more time on core research projects. I have an offer right now from a reputed academic institution with a salary offer in the range of $40,000-$45,000/annum. Unfortunately I am not familiar with the academic environment and I need some feedback on the current trends and whether this is a good offer for my level of experience taking into consideration the current economic conditions. To give you more information, I am highly interested in the research project and I am provided with a competitive benefits package. What are some of the options for future career growth for research specialists 1) if they stick to academic research 2) if they wish to diverge to an industrial career? Thank you for your time and attention. Could you give me some pointers on what aspects to consider when considering an academic job offer?
by KamalRawal at 04-30-2012, 06:19 PM

Our research group under the leadership of Dr. Kamal Rawal (PhD, Bioinformatics) has been working on several bioinformatics projects. We have made significant contributions in the area of bioinformatics. Our research is at par with leading universities in the world. Our recent publication(s) in highly reputed journals such as Nucleic Acids Research speaks volumes about how much we value quality research. Here we mined several hundred GBs of genomic data, discovered patterns and developed software pipeline. Prior to that, we have published in several international journals majorly in the area of computational genome analysis and text mining. In most of these research studies, perl and bioperl has played a major role in method development, algorithm implementation, data extraction & analysis, parsing, automation, software development etc. Every year we receive several applications from students of reputed universities to learn perl, bioperl and do project in our lab. Considering this, we would like to share our learning and expertise in the area of Perl and bioperl with others through this summer school.

A) Skill based training on perl and bioperl (Module 1)
B) Hands on Training on live projects pertaining to genome analysis, automation, large scale data integration, working on giga bytes of data using perl scripts, using super computing facilities, working knowledge of linux for perl, bioperl, design and implementation of algorithms, text mining, network biology etc. (Module 2)
C) Working on live project under expert bioinformaticians. (Module 3)
This Summer School is aimed at early-stage researchers (B. Tech, BSC, MSC, PhD students, postdocs and clinician-scientists) with little or no experience in computational biology, perl bioperl etc, and will deliver a broad understanding of bioinformatics research tools currently available. This school will also expose students to fine nuances of perl & bio perl programming and its application in projects such as genome annotation, text mining and systems biology.

When: Jun 12, 2012 to July 7, 2012
Where: Jaypee Institute of Information Technology, Noida , India

Major Lectures
10 AM till 12 noon every week days. Rest of the time will be for practical trainings

The course will provide practical, hands-on training in bioinformatics as well as in perl/bioperl in the context of the latest biomedical and biological research, as well as serving as a forum for the interchange of ideas and expertise between various participants.

To optimize practical training and interaction between participants and trainers, places on the Summer School are limited to 40.
The programme will provide:
• A broad introduction to perl, bioperl and bioinformatics data resources (through lecture- and practical-based sessions)
• An understanding of when, why and how to use public data resources for molecular biology
• Practical experience of using perl and bioperl , using a range of widely applicable case studies

This is a self supporting summer school with 5 seats offered as free to meritorious students.

Deserving and meritorious students will be provided scholarship to attend this program. They must write an essay -:

"Given my background and interests how this course will help me to enhance my skills"
" Why I should be given chance to attend this summer school ?"

Proceeds- The proceeds or revenue generated shall be donated to setting up of High performance computing facility for bioinformatics research at JIIT Noida under the Department of Biotechnology.

Cost for students/academic-
A) Module 1– 5000 Rs per applicant
B) Module 2- 4000 Rs per applicant
C) Module 3- 3000 Rs per applicant

Cost for Corporate-

A) Module 1 – 15000 Rs per applicant
B) Module 2- 14000 Rs per applicant
C) Module 3- 10000 Rs per applicant

SPECIAL DISCOUNT AND SLOTS FOR JAYPEE STUDENTS!!! All three modules at just Rs.5000/- !!!

To help students pay less or get discounts or even make it free, we are also attempting to get sponsorship from corporate entities as well as funding from government bodies to fund this entire school. So apply, if you are deserving & passionate we will try to admit you. So send applications to email listed below.

The enrolment may be done independently for each module.

Outstation participants shall be assisted in finding accommodation. The hostel facility might be extended to candidates depending upon necessary approvals from university administration Excellent food at nominal cost (Rs 30 per meal) is available at JIIT cafeteria.

Please note: In case number of applications exceed the available slots then seats will be awarded on merit and applicants must submit a completed application form as part of the registration process.

Last date for Applications: 15th May,2012

There will be possibility of guest lectures of experts from various universities under this program.

Key Trainer

Dr. Kamal Rawal (PhD, Bioinformatics) JNU
He has been working on perl and bioperl for the past 10 years. You may read his profile at:

Email your CV to:
by jammy0 at 04-30-2012, 01:20 AM
What would be a potential application of gene therapy for raising the body's baseline testosterone levels in men????
I was thinking whether it would be possible in the near future for gene therapy to work on the hippocampus in increasing the amount of GnRH released and thus LH and testosterone. Any thoughts?????
by mad785 at 04-26-2012, 08:31 AM
I am developing a directory of websites related to biotechnology and would like to include blogs, personal websites, sites of research centers and groups or companies, provided they have content related to biotechnology.
Anyone interested can contact me by email:
Would also welcome some help and feedback on the categories and hierarchy.
thank you
by Subbaraogvlp at 04-21-2012, 04:27 AM
we are not giving any training programs.


Biomed informatics,

by coatespt at 04-18-2012, 08:29 AM
I would like to get some algorithmic wisdom on alignment/matching techniques (my field is computer science, not biology, so please allow for a degree of ignorance!) I'm trying to assess whether an algorithm developed for another purpose might be useful in biotech. Here is my complicated multi-part question, and thanks in advance for your patience!

Background: The basic task is finding out where, in a very large search string, reasonably good alignments for a target string occur. A bio-example might be, you're looking for 2kbp target in in a multi-gig genome, and you want to find any places where that target string occurs, even if it's pretty badly corrupted. (I'm assuming that actually aligning the target and the match will be a separate task executed by one of the standard heavyweight algorithms.) The result is the location of substrings that are less than some given edit-distance from the target string.

My first question is, how fast does FINDING the location of such matches (as opposed to actually aligning them) have to be, in order to be useful to biology problems? Answers either in big-Oh notation or clock time would be helpful. For example, if you had a 5Kbp target, and you wanted to find out everywhere something similar appears in a set of genomes, how fast would an algorithm need to be to be useful?

My second question is, in practical biological applications, over what kind of ranges of goodness/badness are matches interesting, and over what size ranges? E.g., what might be the biggest edit differences that are still of interest in real-world biology problems? Do biologists want only very close matches, or are highly corrupted versions also of interest?

The reason for asking is that I'm curious whether an algorithm originally developed for a different purpose might have biology applications. The algorithm has a one-time linear time pre-processing step, but thereafter is super-linear for actually finding matches. It's only applicable to larger targets, say, minimum of half-kilobyte up to megabytes. Settings for sensitivity, target-size, and the maximum degree of corruption matter somewhat, but as a vanilla example, on a single processing thread it takes about 3 seconds to find matches for a 5kbp target in the c. elegans genome. The same search against the human genome is about 10 minutes. It's parallelizes well though, so within reason, you can just divide by the number of cores you apply.

If you got this far, thanks for reading, and any answers or comments would be greatly appreciated!

by Shwetank Bhardwaj at 04-11-2012, 11:00 PM
Hello friends ! i have done B.Tech with Biotechnology.i want to learn all important techniques & need some industrial experience to update myself as per to get placed in a well reputed company.what should i do next for better carrier in biotechnology.i think in india biotechnology is really suffering a lot...plz tell me the solution....Sad
by amulya at 04-11-2012, 07:00 PM
could anyone suggest me which university to opt for among the following to pursue my master's in biotechnology.
1. san jose state university, california
2. california state university, fresno
3. california state university, channel islands
4. university of texas, san antonio
thank you
by loshu48 at 04-11-2012, 08:02 AM
I am a senior in high school and am currently taking a medical biotechnology course in Hawaii. My medical biotechnology class is currently doing a project in which I am required to conduct a brief interview via e-mail or whichever method you prefer with a researcher or scientist currently employed by a Biotech company. I was wondering if there was anybody currently working at at a biotech company who could be available (I can completely work around your time) for the brief interview. The questions are fairly basic and will just ask about different aspects of working in the labs/skills needed/ working environments etc.
If you have any questions please feel free to contact me at
Thank you
by ph_yasir at 03-29-2012, 01:11 AM
Hi ,

I have an exam and need answers for the following two questions about the quality control of biopharmaceutical drugs:

1- Explain why biological drugs are considered to differ from synthetic chemical drugs.

2- Discuss reasons why the specification and analysis of biological drugs differs from that for chemical drugs
by Pushing at 03-26-2012, 08:46 PM

I'v been reading a few papers about the (relatively) newly discovered phylum Acidobacterium. From what iv read it seems like any organism from this phylum would be a safe bet for antibiotic production. Large genome, soil dwelling organism, production of PKS. In spite of its being hard to culture. Yet i can’t find any papers on subjects. Im tempted to have a go my self. Big Grin
by Sinaeh at 03-25-2012, 08:42 AM

I am writing a paper on the genetically modified papaya (55-1), engineered to contain a coat protein gene of the papaya ringspot virus.. As far as I understand, this gene is used for cross protection (use of a mild virus variety to protect the plant against damage caused by the more severe variety of the same virus)

Here is my question! I have to explain the process of how it was engineered, and so far found information that describes how a agrobacterium tumefaciens plasmid was used, containing the coat protein and a few antibiotic selectable markers. However, in the same paragraph, I also read that the plasmid DNA was added to the papaya genome by "particle bombardment" - which would be the use of a gene gun.

So, is it possible to use both methods or am I misunderstanding the process?

Also, could someone explain to me what exactly promotors and cassettes are and how they are used to engineer the plant?

Thank you so much!

by genhunter at 03-22-2012, 02:44 AM
Hi, Does anyone know what had caused the recent 3x price increase for bottled media? I used to be to buy a 500 ml DMEM for ~$6.00 last year. Now it is ~$18.00. This happens when our research dollars shrinks.

SOOO Frustrating!
by angelllee0113 at 03-18-2012, 12:50 PM
Well, I'm using catechin for my polyphenol oxidase assay to determine the substrate specificity. But the problem is when I try to use 50mM above, the concentration seems to be very high which the spectrophotometer shows more than 4.500. What should I do?? I couldn find any info from the website or journals. Should I dilute it? And I should dilute the substrate only or together with the enzyme? Please help me ! Thanks a lot !!Sad
by MortenHTX at 03-15-2012, 04:59 AM

I have a assignment in my school were i have to explain the expressions trans-gene and cis-gene. I already explained what trans-gene means in my assignment but i don't know about cis-gene. I already looked it up at the Internet and in my biotech-books with no luck. Please help!

Best regards,

Morten Jarlak
by Patrycja at 03-12-2012, 06:06 PM
Dear All,

I would like to recommend you the new service platform Central European Biotechnology Portal - dedicated to the Companies/Institutes/Organizations from Life Science and Drug Discovery sector.

It is an efficient tool that saves time and costs enabling companies/institutes easily search for appropriate business partners and present their services.

Best regards,
CEbiotech Team
by Ijaz_17 at 03-11-2012, 07:10 PM
Hey all,
I am a relatively new user to this forum. I joined because this was an excellent opportunity to gain opinions from other students, professionals like me around the world. I live in India, doing my fourth year in M.Sc(Integrated) - Biotechnology, and I am looking for opportunities where I can do a Summer Internship/Training program for May-June,2012. Though, I have come across many Companies and Institutes offering the same, I would like some additional Info, especially about centres, where you needn't pay.
I would be really greatful, if you can post your opinions here. Smile

Take care.
by roshni at 03-07-2012, 03:36 PM
hello guys'
i m working on my final year project,,,stuck at the final stage of it.
can any1 tell me how to precipitate a polysaccharide(xanthan gum) from a fermentation media effectively !!!
by merai at 02-23-2012, 01:58 AM
I have a problem with rabbits, because recently I produced policlonal antibodies in rabbit and after that he has a strange bone or marrow illness. If it possible that high amount of antibodies in rabbit's blood may affect the animals?
I will be gratefull for any help in that case.
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