[ExpertScie]

The study of understanding the function of various genes and other related parts of the genome is known as functional genomics.
To understand the Human Genome at molecular level is just the first step of Human Genome Projects. There are many questions which are still unanswered related to almost 30,000 genes. The research in this is further required to understand the role of single nucleotide polymorphisms also known as SNP’s. Such another unsolved question is complete role of non-coding regions in the genome.
This project Human Genome which is working to understand various functions of genes is also collected data to describe gene or protein functions and their interactions. This study focus on vast concepts of human genomes especially related to transcription, translation and interactions. The first goal of functional genomics is to study the relationship of an organism’s genome and its phenotype. This study is to further expand and develop genomics and proteomic knowledge. The various techniques used in this are Genetic interaction mapping, Microarrays, serial analysis of gene expression that is SAGE, Yeast Two Hybrid, Protein- Protein interaction, Affinity purification, mass spectrometry.
In functional genomics study, the functional annotation for genes is done by methods like Genome annotation, Rosetta stone approach which is a scientific method which employs computers in de novo protein function predictions.