08-29-2013, 04:17 PM
Organ Transplantation has been an important part especially in the field of regenerative medicine. It is amazing how both science and technology can help many lives either live a little bit longer or live their lives to the fullest because of this.
Organ transplanting has a long and rich history. Before successful operations took place, doctors had to deal with rejection, especially infection, and even death.
Aside from the common internal organs being a necessary transplant, there were also interesting parts of the body which were transferred. There were jaws, hands, arms, legs, and even reproductive organs.
There are different types of transplants which were partially discussed in the article above.
One of them is the well-known autograft, where the tissue comes from the same individual. This procedure is usually performed with surplus tissue, regenerative tissue, or tissues that are more needed in other areas.
Allograft, on the other hand, is the type of transplant between 2 genetically non-identical members of one species. Transplant rejection is most common in this case. Such is measured using the Panel reactive antibody level.
Isografts are subsets of allografts which are done between identical twins. They are anatomically identical to allografts, however they do not spark an immune response.
Xenografts are transplants of those between different species. Such procedures are generally dangerous as there is more risk in rejection, non-compatibility and even spread of disease.
Another is the split transplant. This is so when an organ is separated but transplanted into two different individuals. However, transplanting an entire organ is better and has been more successful.
The domino transplant is done to patients where when an organ needs to be replaced, but the transplanting of one of its healthy organs is better or sometimes needed. Such as in the case of patients with cystic fibrosis, where both the lungs and heart produce a higher rate of success in the operation, even if only both of the lungs are affected. The heart of such individual can be transplanted to another.
Lastly, we have the ABO-incompatible type of transplants. These are usually done to infants (under 12 months) or those before the age of two where their immune system has not yet developed fully.
Organ transplanting has a long and rich history. Before successful operations took place, doctors had to deal with rejection, especially infection, and even death.
Aside from the common internal organs being a necessary transplant, there were also interesting parts of the body which were transferred. There were jaws, hands, arms, legs, and even reproductive organs.
There are different types of transplants which were partially discussed in the article above.
One of them is the well-known autograft, where the tissue comes from the same individual. This procedure is usually performed with surplus tissue, regenerative tissue, or tissues that are more needed in other areas.
Allograft, on the other hand, is the type of transplant between 2 genetically non-identical members of one species. Transplant rejection is most common in this case. Such is measured using the Panel reactive antibody level.
Isografts are subsets of allografts which are done between identical twins. They are anatomically identical to allografts, however they do not spark an immune response.
Xenografts are transplants of those between different species. Such procedures are generally dangerous as there is more risk in rejection, non-compatibility and even spread of disease.
Another is the split transplant. This is so when an organ is separated but transplanted into two different individuals. However, transplanting an entire organ is better and has been more successful.
The domino transplant is done to patients where when an organ needs to be replaced, but the transplanting of one of its healthy organs is better or sometimes needed. Such as in the case of patients with cystic fibrosis, where both the lungs and heart produce a higher rate of success in the operation, even if only both of the lungs are affected. The heart of such individual can be transplanted to another.
Lastly, we have the ABO-incompatible type of transplants. These are usually done to infants (under 12 months) or those before the age of two where their immune system has not yet developed fully.
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