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Thread: Rare codons in the N-terminal region enhance protein expression
Post: Rare codons in the N-terminal region enhance prote...
Although the Central Dogma was first stated by Francis Crick over a half-century ago, we're still learning exactly how transcription and translation are orchestrated in cells. A recent Science paper r...
Forum: News
03-20-2014, 01:10 PM
Thread: 3 Critical Proteins for Maintaining Stem Cells in Culture
Post: 3 Critical Proteins for Maintaining Stem Cells in ...
STAP (Stimulus-triggered acquisition of pluripotency) cells have made recent science headlines with reports that mouse somatic cells can be reprogrammed into pluripotent cells simply by being subjecte...
Forum: News
03-18-2014, 03:45 PM
Thread: Antibody against clotting factor prevents thrombosis without increasing bleeding risk
Post: Antibody against clotting factor prevents thrombos...
A recent publication in Science Translational Medicine describes the use of a humanized monoclonal antibody against activated FXIIa, identified using phage display, to prevent the formation of blood...
Forum: News
03-17-2014, 05:04 PM
Thread: Improved, traceable membrane protein production in E.coli through tandem fusions and
Post: Improved, traceable membrane protein production in...
Membrane protein expression remains a bottleneck in its characterization and structure determination. In a recent study, scientists created a robust strategy to increase the probability of membrane pr...
Forum: News
03-14-2014, 04:19 PM
Thread: Crystal structures are still reveal novel features of protein folding & substrate bin
Post: Crystal structures are still reveal novel features...
In a recent paper published in Nature Chemical Biology, new crystal structures provide insights into the evolution and activity of the AdoMet radical enzyme family that plays a critical role in purine...
Forum: News
03-12-2014, 03:38 PM
Thread: Milk does the heart good: Milk-derived peptides exhibit antihypertensive effect
Post: RE: Milk does the heart good: Milk-derived pepti...
(03-11-2014, 08:49 PM)Angelou Wrote: Bioactive peptides trigger certain functionalities such as antioxidative, antimicrobial, antihypertensive, cytomodulatory and immunomodulatory activities in the ...
Forum: News
03-12-2014, 03:37 PM
Thread: Milk does the heart good: Milk-derived peptides exhibit antihypertensive effect
Post: Milk does the heart good: Milk-derived peptides ...
Bioactive milk peptides have potential in the treatment of a number of ailments including cancer and diabetes. In a recent publication, orally administered milk-derived peptides were shown to survive ...
Forum: News
03-11-2014, 06:14 PM
Thread: Immunoproteasome inhibitor treats multiple sclerosis
Post: Immunoproteasome inhibitor treats multiple scleros...
For over a decade, the development of potent protease inhibitors, like the breakthrough drug Bortezomib, have been an important therapuetic strategy of cancer drug development. Now researchers are ext...
Forum: News
03-10-2014, 04:52 PM
Thread: GenScript Launches GenPlus™ Next-Generation Gene Synthesis Technology, achieving mont
Post: GenScript Launches GenPlus™ Next-Generation Gene S...
GenScript, the world’s largest provider of synthetic genes, has launched a new GenPlus™ Next-Generation Gene Synthesis service, which offers unmatched capacity and cost-efficiency for custom gene synt...
Forum: News
02-28-2014, 05:26 PM
Thread: Protein C Tag Antibody (HPC4)
Post: Protein C Tag Antibody (HPC4)
Protein C (HPC4) tag encodes residues 6 through 17 of the protein C heavy chain. Compared with the His tag, Protein C tag can capture higher purity proteins from Escherichia coli, yeast, Drosophila,...
02-24-2014, 06:34 PM
Thread: E.coli mRNA breakdown results in dramatic improvements in recombinant protein produc
Post: E.coli mRNA breakdown results in dramatic improvem...
MazF is an E.coli enzyme that degrades cellular mRNA in a targeted fashion, at the "ACA" sequence. By modifying all "ACA" triplets in the target gene, a study showed that induction of MazF toxin cause...
Forum: News
02-21-2014, 03:41 PM