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Engineered "Twincretin" peptide containing both GLP-1 and GIP sequences reduces obesi
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This study had begun from United State where researchers observed the practical over Mice and many other animals. University of Florida conducted this research and produced a pray which was speedily losing the weight of animals. The university researcher hold the view that the role of Pepetite GP-1 lasts incretin effects on the subject due to greater stimulation effects over insulin secretion. It controls reduction of food intake, regulation of postprandial glucagon, slow gastric emptying, and enhancement to glucose dependence. This treatment has been centered on augmenting the availability of insulin in the body. Either directly administration of insulin or through the oral mechanism which is responsible for insulin secretion. These mechanisms do not result in hypoglycemia. Besides, Researchers of University of Copenhagen tried to determine the effects of glucagon peptide 1 receptor (GLP-1R) for weight loss. After thoroughly studying the matter while investigating cholesterol, liver enzyme levels, blood sugar and blood pressure, they concluded that if its doze is over taken, it may result in side effects. The patients who were researched during the process had side effects of vomiting, diarrhea, and nausea.
On the other hand, these researchers hold the view that additional benefits can also be achieved through GLP-1 like reduction in cholesterol level and blood pressure. Not only this, they also opine that when GLP-1 is given to obese patients without or with diabetes, it may result in clinically beneficial effects over the body weight. Professor Raj Padwal of University of Alberta writes the same remarks as stated by the researchers of Copenhagen. But he discloses an uncertainty over the safety of GLP-1 agonist. The research over Glp-1 is still in process in different universities and researchers are trying to identify the possible and temporal effects which may have some hidden and drastic impacts. But, it is right in saying that it has the ability to reduce the weight immediately and abruptly.
Sasa Milosevic
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RE: Engineered "Twincretin" peptide containing both GLP-1 and GIP sequences ... - by sale0303 - 01-05-2014, 10:50 AM



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