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Animal pharming is the newly evolving field of genetic engineering which deals with the use of transgenic animals in the production of Pharma products (Bio Therapeutics) for treating various human diseases. Listed below are some of the transgenic animals and their application in pharmaceutical research.

Transgenic Mice: First transgenic mouse was developed in the year 1974. Genetically modified mice are employed as models in various research studies carried out in order to find cure for human diseases like cardiac problems, cancer, diabetes, arthritis and age related disorders.

Transgenic pigs: Xenotransplantation, Factor 8 and factor 9 , Tissue plasminogen activator, genetically engineered enviro pigs with the newly developed ability to generate the enzyme phytase by the salivary glands which in turn digests the phosphorous present in its feed thus making its excreta a eco friendly manure and hence the name “Enviro Pigs”. Research is going on to develop a protein based surgical bandage from transgenic pigs.

Transgenic sheep: Alpha I Anti Trypsin(emphysema), CFTR(Cystic fibrosis), Factor 8 and Factor 9(Hemophilia), Human protein C(Thrombosis)

Transgenic Goat: Human protein C and anti thrombin 3 against thrombosis, glutamic acid decarboxylase for Type I diabetes, Pro 542 to treat HIV infection and monoclonal antibodies to develop vaccines. Also extraction of spider silk like protein from transgenic goat’s milk proves to be a mile stone. The anticoagulant drug Atryn holds the credential of being the first bio Pharma approved by FDA in the year 2009.

Transgenic Cow: The bio therapeutics derived from transgenic cows includes alpha lactalbumin, factor 8, fibrinogen, Collagen I and II, lacto ferrin and human serum albumin and also monoclonal antibodies.

Transgenic Dog: In 2009, the study to find out the role of estrogen in fertility employed the use of genetically engineered dogs. The experimental dogs were genetically engineered with the insertion of a gene responsible for fluorescent glow in the dogs which changed its colour to red while exposed to UV light.

Transgenic cats: Green-fluorescent transgenic cats were developed in the year 2011 in order to explore various therapeutics for treating HIV infection (humans) and FIV infection (cats).