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+--- Thread: Antibody against clotting factor prevents thrombosis without increasing bleeding risk (/thread-3234.html)
Antibody against clotting factor prevents thrombosis without increasing bleeding risk - Genscriptlorraine - 03-17-2014
A recent publication in Science Translational Medicine describes the use of a humanized monoclonal antibody against activated
FXIIa, identified using phage display, to prevent the formation of blood clots without increasing the risk of bleeding. Preventing
thrombus formation while using a bypass system often leads to unwanted bleeding, sometimes in the brain, making this breakthrough
treatment an attractive alternative to heparin.
GenScript offers Custom mAb production services to develop your specific antibody and Antibody Library and Phage Display services
which can build a library with up to 1010 individual clones.
RE: Antibody against clotting factor prevents thrombosis without increasing bleeding risk - Angelou - 03-18-2014
Well, all these drugs also entail an increased risk of bleeding in patients that partially offsets their beneficial effects.