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Acidobacterium, Where has all the reserch gone? - Printable Version

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Acidobacterium, Where has all the reserch gone? - Pushing - 03-26-2012

Hello

I'v been reading a few papers about the (relatively) newly discovered phylum Acidobacterium. From what iv read it seems like any organism from this phylum would be a safe bet for antibiotic production. Large genome, soil dwelling organism, production of PKS. In spite of its being hard to culture. Yet i can’t find any papers on subjects. Im tempted to have a go my self. Big Grin


RE: Acidobacterium, Where has all the reserch gone? - MarkLiles - 07-18-2012

(03-26-2012, 08:46 PM)Pushing Wrote: Hello

I'v been reading a few papers about the (relatively) newly discovered phylum Acidobacterium. From what iv read it seems like any organism from this phylum would be a safe bet for antibiotic production. Large genome, soil dwelling organism, production of PKS. In spite of its being hard to culture. Yet i can’t find any papers on subjects. Im tempted to have a go my self. Big Grin

I couldn't agree more!
We have a collection of Acidobacteria cultures, some of which are published (http://aem.asm.org/content/early/2011/09/23/AEM.05956-11.abstract) and are working on characterizing secondary metabolites they produce. We are also working toward expressing soil metagenomic libraries (and specific large-insert clones that have PKS pathways) within an Acidobacteria host. If you're interested in learning more or helping on this project please let me know.
best regards,
Mark Liles (lilesma@auburn.edu)



RE: Acidobacterium, Where has all the reserch gone? - davidflora - 09-15-2012

Yes please infact i am also interested in your project.As the subject of my topic is similar to you.It would be great help to you if you will give me your valuable information.


RE: Acidobacterium, Where has all the reserch gone? - MarkLiles - 09-16-2012

(09-15-2012, 02:47 PM)davidflora Wrote: Yes please infact i am also interested in your project.As the subject of my topic is similar to you.It would be great help to you if you will give me your valuable information.

I'll be glad to correspond about this David, please send an email to my address at lilesma@auburn.edu and indicate your specific interests in Acidobacteria, and we can see how our interests intersect.
Mark


RE: Acidobacterium, Where has all the reserch gone? - Thomast22 - 10-04-2012

A growing number of Acidobacteria strains have been isolated from environments worldwide, with most isolates derived from acidic samples and affiliated with subdivision 1. We recovered 18 Acidobacteria strains from an alkaline soil, among which 11 belonged to the previously uncultured subdivision 6. Various medium formulations were tested for their effects on Acidobacteria growth.